Watch Jamie Lee Curtis Tell Homophobes and Transphobes to ‘Back the F*ck Off’

Related: Jamie Lee Curtis’ Trans Daughter, Ruby Guest, Opens Up About Coming Out

The Everything Everywhere All at Once star also spoke about her recent controversy over the Israel-Hamas War. “I am also human and therefore flawed and contradictory, and I make mistakes, and I try to own them in this time of great conflict around the world, where we are all trying to find our individual center of care and compassion and outreach so we can use our voices amidst the cacophony of hate that is surrounding us,” she said.

She concluded by taking a dig at the state of LGBTQ+ rights in the U.S. and thanking the other advocates in the room.

“I pray that homophobia and transphobia that is being championed in the name of religion by the right is exposed and silenced as wrong,” Curtis said, “by the love of humanity that is the center of our gay and our trans community.”